Study the Relationship Between Vitamin E and Some Biochemical Changes in Patients with Type 2 Diabetes Mellitus

H.N.Al-Rubae, Salwa

	Study the Relationship Between Vitamin E and Some Biochemical Changes in Patients with Type 2 Diabetes Mellitus
Al-Mustansiriyah Journal of Science
Article 1, Volume 21, Issue 5, 2010, Pages 234-243
Author
Salwa H.N.Al-Rubae
Abstract
The present study is an attempt to assess the serum levels of vitamin E, γ- GGT.CRP, total cholesterol, and fasting glucose in patients with type 2 Diabetes Mellitus and compare the results obtained with healthy controls group, and to ascertain the relationship between the antioxidant vitamin E with some associated parameters. Type 2 diabetes mellitus group include 30 patients (18 male and 12 female) who were selected from patients attending Specialist Center for Endocrine and Diabetes in AL-Kindy Hospital in Baghdad. The control group included 30 healthy subjects (15 male and 15 female). Fasting glucose level in patients with T2DM was (7.39+3.095 mmol/L).The results reveal there were no significant differences between T2DM and control in age.The present study shows that the means for BMI (20.13+1.79 kg/m2), γ- GGT (41.95+6.012 U/L), cholesterol (201.36+38.17mg/dL), vitamin E (0.565+0.178 mg/dL), and vit.E/TC (0.003+0.001) were significantly differences in T2DM as compared to control group. CRP levels were negative (<0.6 mg/dL) in 12 patients and positive (>0.6 mg/dL) was (2.07+2.066 mg/dL)) in 18 patients.Furthermore, serum vitamin E concentrations showed significantly positive relationship with the ratio of vit.E/TC, and negative significant relationship found between vitamin E and BMI, fasting glucose, and γ- GGT. While non significant positive relationship found between vitamin E and both of cholesterol, age and CRP.

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