A. Turky, Z., A. Ahmed, S. (2014). Preparation of Some 1,2,4-Triazol Schiff Bases as Urease Inhibitors and Study Their Effect on Proteus Mirabilis Bacteria. , 17(4), 44-50.
Zahraa A. Turky; Salman A. Ahmed. "Preparation of Some 1,2,4-Triazol Schiff Bases as Urease Inhibitors and Study Their Effect on Proteus Mirabilis Bacteria". , 17, 4, 2014, 44-50.
A. Turky, Z., A. Ahmed, S. (2014). 'Preparation of Some 1,2,4-Triazol Schiff Bases as Urease Inhibitors and Study Their Effect on Proteus Mirabilis Bacteria', , 17(4), pp. 44-50.
A. Turky, Z., A. Ahmed, S. Preparation of Some 1,2,4-Triazol Schiff Bases as Urease Inhibitors and Study Their Effect on Proteus Mirabilis Bacteria. , 2014; 17(4): 44-50.

Preparation of Some 1,2,4-Triazol Schiff Bases as Urease Inhibitors and Study Their Effect on Proteus Mirabilis Bacteria

Journal of Al-Nahrain University - Science
Article 1, Volume 17, Issue 4, 2014, Pages 44-50
Authors
Zahraa A. Turky; Salman A. Ahmed
Abstract
The basic nucleus 4-(amino)-5-phenyl-l-4H-1,2,4-triazole-3-thiol was prepared by cyclisation of potassium dithiocarbazinate with hydrazine hydrate using ethanol as solvent under reflux condition for 3-4 hrs.. The compound which has been synthesized successfully was subjected to addition reaction with different aldehydes to synthesize Schiff bases. The compounds were confirmed by[ physical parameters (solubility, melting point),1H nuclear magnetic resonance (1HNMR)and spectroscopic methods (FTIR)]. All the synthesized compounds were screened for their urease inhibition. Some compounds showed excellent urease inhibition activity.
Keywords
triazol ring; triazol Schiff base; urease inhibitors
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