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Nutritional and Neurological Assessment in Adult Patients with Celiac Disease | ||
| Medical Journal of Babylon | ||
| Article 1, Volume 11, Issue 4, 2014, Pages 938-960 | ||
| Authors | ||
| Sura Talal Younis; Hadeel Fadhil Farhood; Moshtak A. Wtwt | ||
| Abstract | ||
| Celiac disease is a chronic inflammatory, autoimmune disorder characterize by malabsorption of nutrient after ingestion of gluten, it is prevalence nearly 1% in many country, clinical manifestation either gastro intestinal manifestation such as diarrhea, abdominal pain, bloating, weight loss, constipation, or non-gastro intestinal manifestation such as anemia, neuropathy and unexplained infertility. The aim of this study is to assess the nutritional status and determine the diet satisfaction & burden of gluten-free diet therapy in celiac patients also to assess the autonomic and peripheral neuropathy in those patients. This was Cross-sectional study conducted in gastroenterology and HepatologyCenter atMarjan Medical City in Babylon province,Hilla city, from 15th February 2014 to 31 of May 2014. All patients included were proved celiac and on gluten-free diet. Data obtained included questionnaires, measurement which includes body mass index, nerve conductive study, blood pressure in response to standing position and hand grip and heart rate in deep breathing with laboratory investigation includes complete blood count, serum albumin, serological test of celiac disease. The study included 70 patient, were 45 are female and 25 are male whose mean age was (30.67± 9.72) years old. of those 34.3% were underweight and 65.7% were not underweight (normal 51.4%, overweight 11.4%, obese 2.9%) , 18.6% of all included patient had family history of celiac disease, while the percentage of patients whose suffer from diarrhea, abdominal pain and problem in the feet (pain, numbness, tingling) were 60%, 64.3%, 37.1% respectively and 57.1% had anemia, 29.1% of married female had unfavorable outcome of pregnancy and 17.3% of married female and male had unexplained infertility. Regarding the neuropathy 34.3% had autonomic neuropathy and only 2.9% had peripheral neuropathy. According to diet satisfaction and burden of gluten free diet there was statistical significant association between BMI and history to make menus, not being able to eat same foods as other family members, feeling satisfied after meals and feeling that the health condition is good. In the finding of present study there are high percentage of underweight in contrast to overweight and obesity in patients with celiac disease with high prevalence of anemia mainly iron deficiency anemia and also shows high prevalence of autonomic neuropathy compare to peripheral neuropathy, the celiac disease may be the one cause of unexplained infertility and unfavorable outcome of pregnancy. Regarding the diet satisfaction and burden of gluten free diet, most of the patients with underweight had no history to make menu and feeling not satisfied after meal and health condition is not good and most of celiac patient had burden of cooking gluten free diet. | ||
| Keywords | ||
| celiac disease; nutritional assessment; peripheral neuropathy; autonomic neuropathy | ||
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