Effect of Aspirin on Sperm Specification and Some Hematological Parameters  in Male Albino White Rat

S. D. Al-Taei, Bilal

	Effect of Aspirin on Sperm Specification and Some Hematological Parameters in Male Albino White Rat
Jornal of Biotechnology Research Center
Article 1, Volume 8, Issue 4, 2014, Pages 34-38
Author
Bilal S. D. Al-Taei
Abstract
Thirty male albino rats were divided into three groups, the first group was given aspirin at a dose of 25 mg / kg orally and twice a day, the second group dosage was 125 mg / kg at the same way, the third set group which considered as control was treated with physiological saline, each group took 0.5 ml amount. The period of experience took four weeks at the end of the experience, in the day 29the animals were anesthetized and eradicated the epididym is and calculated the total number of sperm and percentages of viable and dead sperm as well as the percentages of motile and non-motile sperm, the blood was taken for hematological tests, results confirmed the existence of a decreased significant value (P<0.01) in the total number of sperm of the 2nd group compared with control group and the decline value was less significant (p<0.05) in the first group compared with control group. In addition a significant value (P<0.01) increased in the percentage of dead sperm and non-motile sperm, also a significant value (p <0.01) decreased in the percentage of viable sperm and motile sperm, while the results proved the existence of a significant value (p<0.05) reductions in PCV, Hb, TWBC and monocyte values compared with control group. effect of aspirin on the male reproductive system may be due to being a Prostaglandins inhibitor, and These findings probably indicate that aspirin have deleterious effect on the blood chemistry of male albino rats.
Keywords
Aspirin; Sperms; hematological parameters

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