The Role Of Tumor Markers In The Diagnosis And Follow UpIn Patients With Pancreatic Cancer

Aladdin Al-Bayatti, Ansam

	The Role Of Tumor Markers In The Diagnosis And Follow UpIn Patients With Pancreatic Cancer
Journal of the Faculty of Medicine
Article 1, Volume 48, Issue 4, 2006, Pages 421-424
Author
Ansam Aladdin Al-Bayatti
Abstract
Background: To shade a light on certain tumor markers and their sensitivity and specificity in determination of pancreatic cancer.Patients & Methods :- A total of 35 patients with pancreatic cancer were studied between June 2003 and April 2004 in Specialized Surgical - Baghdad Teaching Hospital . These patients were compared with other 25 non malignant G.I diseases patients as well as 35 healthy controls . The serum was estimated for CAI 9-9 , and CEA by ELFA (Enzyme Linked Fluorescent Assay) method and CPR by ELISA method.Results :- Five patients with pancreatic cancer were excluded from this study because they were beyond surgery.The results show that there is significant differences between serum level of CAI 9-9 in pancreatic cancer patients as compared with the non malignant G.I disease patients group and control (P< 0.05). While for the determination of CEA there is also significant difference between the pancreatic patients group as compared with the non malignant G.I patients group and control group (P< 0.05). As for the result of CRP there is also significant difference between the pancreatic patients group and the non malignant G.I patients group and control group (P< 0.05) .Conclusion :- Significant differences were found in the result of the tumor markers CA 19-9 , CEA , and CRP studied in patients with pancreatic cancer as compared with the other non malignant G.I patients and controls . The sensitivity for using all the mentioned parameters was 90% were as the specificity was 75%
Keywords
Pancreatic tumors; CEA; CRP

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