Chromosomal Aberrations In Patients With Recurrent Spontaneous Abortion

Abdul.wahed, Rafid

	Chromosomal Aberrations In Patients With Recurrent Spontaneous Abortion
Al-Mustansiriyah Journal of Science
Article 1, Volume 21, Issue 6, 2010, Pages 268-274
Author
Rafid abdul.wahed
Abstract
This results detected the chromosomal aberrations has important role in spontaneous absortions for parents which suffered from chromosomel aberrations. acytogenetic factors are found to show association with recurrent spontaneous abortions RSA. In approximately 2-4% of couples with recurrent pregnancy loss, one partner will have a genetically balanced structural chromosome rearrangement. Couples who are predisposed toward chromosomal abnormal conceptions will be at increased risk for Recurrent Spontaneous Abortion. In this study an evaluation of the contribution of chromosomal anomalies in causing repeated spontaneous abortions was made. This study included 32 couples(64 individuals) with a history of repeated spontaneous abortion who were referred for cytogenetic studies at the cytogenetic Department from the educational laboratory in Al-Yarmook hospital in Baghdad for hormonal of Biochemical analysis which Considered in normal range of health persones. All the other clinical parameters of both the partners were within the normal range. The results showed numerical aberrations, in chromosome 6 and 15. The numerical aberrations, included a trans location also chromatide breacks in sex and somatic chromosomes when compared with health persones males or female. Chromosomal analysis is an important etiological investigation in couples with repeated spontaneous abortions as it helps in genetic counseling and deciding about further reproductive options. and associated with an increased risk of spontaneous abortion. Corresponding author: Rafid Abdulwahid Biochemical engineering Dept, Al-khwarizimi collage engineering, Baghdad University .

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