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VAGINAL MISOPROSTOL FOR SECOND TRIMESTER PREGNANCY TERMINATION IN WOMEN WITH PRIOR ONE CAESAREAN DELIVERY | ||
| IRAQI JOURNAL OF MEDICAL SCIENCES | ||
| Article 1, Volume 12, Issue 3, 2014, Pages 238-244 | ||
| Author | ||
| Enas A.A. Al-Kazaaly | ||
| Abstract | ||
| Background:Misoprostol, a synthetic prostaglandin analogue, has become the leading mean for terminating the pregnancy. It is not clear, however, whether misoprostol is a safe abortifacient after thirteen weeks gestation in women who have a uterine scar from a previous lower segment caesarean delivery. Objective:To evaluate the efficacy and maternal side effects of misoprostol used vaginally for second trimester termination in women with a single previous lower segment caesarean delivery. Method: Sixty participants with a history of previous one lower segment caesarean delivery underwent pregnancy termination for missed abortion or lethal fetal anomaly between 14-28 weeks gestation using intra vaginal misoprostol. The dose of which was 400 microgram up to 20 weeks gestation and 200 microgram thereafter, repeated every 4 hours with a 12 hours nightly rest from misoprostol application up to a maximum of 72 hours. Women having termination for similar reasons but lacking a history of cesarean section served as a control group. Results:Abortion rate was 96.66% in the study group and 95% in the control group. The mean induction to abortion interval was 21.81±9.51 for the study group and 22.21±8.52 for the control group with no significant difference between the two groups. No cases of uterine rupture occurred in either groups. Conclusion:Inducing abortion with lower misoprostol doses appear to be safe and effective throughout the second trimester in women with a single previous lower segment cesarean delivery. Keywords:Second trimester, Misoprostol, Termination of pregnancy | ||
| Keywords | ||
| Second trimester; Misoprostol; Termination of pregnancy | ||
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