EFFECT OF EDIBLE MUSHROOM ON CHOLESTEROL AND LIPID PROFILE  IN MICE BLOOD SERUM

A . Hadwan, H.; H. K.Hillali, A.; K.  Abdullrazaq, A.; T. Al-Kaisay, M.

	EFFECT OF EDIBLE MUSHROOM ON CHOLESTEROL AND LIPID PROFILE IN MICE BLOOD SERUM
IRAQ JOURNAL OF AGRICULTURE
Article 1, Volume 14, Issue 8, 2009, Pages 0-0
Authors
H. A . Hadwan; A. H. K.Hillali; A. K. Abdullrazaq; M. T. Al-Kaisay
Abstract
The study was conducted at the Ministry of Agriculture-Organic fertilizer Laboratories over the period of 2007-2008 for studying the effect of four types of mushroom on the Hypercholesterolemia and hypolipidemic in mice .A total of 240 female weighing 20-25 gm (3 month of age) were randomly allocated to three experiment diets ,four replicates of 15 mice were used for each treatment when soybean meal was replaced by mushroom 0(Tc), 50%replacment(T1) and 100% replacement (T2). Body weight (BW) and feed intake were recorded daily for eight weeks, Blood were collected from heart by heart puncture for assay and determine calculate Total cholesterol. Types of lipoprotein (LDL,HLDL and VLDL) also were determined, total aerobics and anaerobic bacteria and lactic bacteria in intestine were also determined. Data were analyzed by using one way ANOVA by using SPSS program. The Results showed a significant (P<0.05) decrease in total plasma cholesterol and liver, triglycerides and low density lipoprotein. The decrease in all values mentioned above were proportional with increasing concentration of mushroom in the ration. the good cholesterol HDL showed higher level in T2 followed by T1 compared to control treatment (Tc) respectively. Also the results showed a significant decrease in aerobics bacteria and a significant increase in lactic acid bacteria. Also the replacement of soybeans by edible mushroom showed total drop in fat liver and increased fat in feces. Thus, the investigationsuggested that edible mushroom was capable and effective to reduce cholesterol in plasma and regulating fat in body.

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