The effect of chronic exposure to X-ray on some blood parameters and P53 gene on the heart in female albino rats

	The effect of chronic exposure to X-ray on some blood parameters and P53 gene on the heart in female albino rats
journal of kerbala university
Article 1, Volume 11, Issue 1, 2015, Pages 6-15 PDF (0 K)
Abstract
The present study was conducted to investigate the chronic effect of X-ray on the heart. Randomly divided 30 female albino rats into three groups (10 animals / group ) for a period of two consecutive months , considered the first group (T1) as a group control and the second group (T2) exposed to X-rays (80 KV) within one meter / day for a month as well as is the case for the third group (T3) were subjected to a period of two months , After collecting blood samples before and after the experiment was observed significant decrease (0.05> P) in RBC, PCV, Hb and platelet, and high moral (0.05> P) in WBC in the exposed group for a month T2 and the group exposed for two months T3 compared with the control group T1, As for changes in sick textile Heart observed incidence of alienation in the epithelial cell layer and crash cartilage glass and congestion hematoma in rats exposed group for a month T2 and for two months T2 compared with the control group T1, as genetic study indicated increased gene expression for gene P53 to the fabric of the lung in animals exposed for month and T2 Group exposed for two months T3 compared with the control group T1. Inferred from the current study that chronic exposure to x-rays lead to get changes in the standards and the presence of Doll satisfactory effects in heart tissue as well as an increase in the P53 gene expression of cardiac tissue .

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