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Study the effect of commando (Imidacloprid 20%) pesticide residual on the Mice’s liver and kidneys | ||
| Al-Anbar Journal of Veterinary Sciences | ||
| Article 1, Volume 10, Issue 2, 2017, Pages 72-86 PDF (3 M) | ||
| Authors | ||
| E. M. Rasheed; Q. A Ibraheem | ||
| Abstract | ||
| This Study was carried out at the animal house of the Center for Biotechnology/ Nahrain of University to study the effect of the residue of the commando on the mice with giving the mice pesticide orally for thirty days continuously from the pesticide with dose 200 microliters 0.2 ml and observing the changes at the if giving dosage period. Forty-Five mice age two and half months were used, divided roudmaly to three groups (15/ for each group), the first group used which was referred to it by G1 for the comparison purpose, the second group, which was referred to (G2) was give with a concentration of 18.4 ppm for the concentration 160 ppm was used. to add third group referred to (G3) and for the same period, and the several parametol were performed by drawing blood samples and taking the resulting serum from the separation process and also taking samples and also taking from the sections of the tissue of the liver and kidneys by Bancroft method. The results showed that the different doses of the pesticide sequentially showed a significant decrease (p<0.01) in total cholesterol and triglycerides in the two groups (G2, G3) compared with the group G1., and the results showed a significant differences (P>0.01) in the level of triglycerides group (G1) compared to the (G2) and the (control) group G1. No significant differences were observed in the level of high density lipids between G1. group and both (G2, G3) groups compared to G group. Low density lipid protein and very low density in both groups (G2, G3) compared to group G1 The results showed a significant increase. There was a significant increase in urea level in both groups (G2, G3) compare with group G1. The results showed a significant (p<0.01) increase in Creatine level in the animal group compared (G1) and (G2) group and G3. group and the results showed significant differences in the level of uric acid in group G2. compared to the groups of animals treated with pesticide (G2, G3), and the results showed no differences in the level of albumin and Bilirubin in the three groups, and finally, the results showed a significant increase of the (GPT, GOT) level in both groups (G2, G3) compares with G1. group, while the results of both groups (G2, G3) of the histological of the liver showed enlargement and bleeding of the vein and increased rate of division in the nucleus and irregular forms of liver cells and as well as, the occurrence of macular cell degeneration and starch compared to group G1. while the results of the histological sections taken from the kidney showed the emergence of congestion and expansion of blood vessels between the kidneys, and the accumulation of lymphocytes and cortical cells of the inflammatory cells and filtered and the occurrence of bleeding as well as the emergence of sediments | ||
| Keywords | ||
| Commando Pesticides; kidney; liver; mice | ||
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