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Evaluation the inhibitory efficiency of hybrid nano levofloxacin against some gram negative bacteria isolated from diabetic foot ulcer | ||
| journal of kerbala university | ||
| Article 1, Volume 14, Issue 1, 2018, Pages 320-329 PDF (0 K) | ||
| Abstract | ||
| The inhibitory activity of each of nano antibiotic levofloxacin Magnisum-Alaminum –Levofloxacin – Layered Double Hydroxide (Mg-Al-LEV-LDH) and free levofloxacin (LEV) were assessed by diffusion agar method against bacterial isolates Proteus mirabilis , Escherichia coli and Pseudomonas spp. isolated from diabetic foot ulcer. Result showed that highest inhibitory activity was obtained against Proteus mirabilis 17a and 17b isolates with average inhibition zones of 40.535 and 40.035 mm, respectively, while the Escherichia coli 102 isolate was the lowest affected with average zone of 3.464 mm. The antimicrobial susceptibility test was carried out for 14 antibiotics and the results of the bacterial susceptibility to different antibiotics varied depending on the tested bacterial isolates. Amikacin and Imipenem were the most effective antimicrobial agents against Escherichia coli. Generally, high resistance among the tested isolates was detected. | ||
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