- All Journals
- Al-Qadisiyah University
- Basrah University
- Kirkuk University
- Mosul University
- The Iraqi Borad for Medical Specialization
- University of Anbar
- University of Technology
- Al Mustafa University
- Al-Zahraa University for Women
- Alnoor University
- Kunooz University
- Misan University
- Ninevah University
- Tikrit University
- University of Al-Hamdaniya
- University of Kerbala
Synthesis of drug compounds against fungal and bacterial pathogen affecting animal derived from pyranopyrazol compounds | ||
| Al-Anbar Journal of Veterinary Sciences | ||
| Article 1, Volume 3, Issue 1, 2010, Pages 92-99 PDF (163.41 K) | ||
| Author | ||
| M . T . A . Alsa | ||
| Abstract | ||
| This research is performed by synthesis of aseries of a compound derived pyrano pyrazol by means cyclic closing mechanism of the phenylhydrazine and Ethylacetoacetate compound by using sulfuric acid as a catalase to prepare the 3,4 – dimethyl – 1 – phenyl – 1H , 6H – pyrano [ 2-3-C ] pyrazol – 6 – one [A1] compound with the sodium hypochlorate compound to prepare the 5- chloro – 3,4 – dimethyl – 1 – phenyl – 1H – 6H – pyrano [ 2-3-C] prazol -6 – one [A2] compound which is considered a key to other prepared compounds . The structures of the prepared compounds were identified by infra red (I.R), Ultra violet spectra (U.V) and elemental (C.H.N)analysis. The research includes the biological activity of these compounds on different types of bacteria & fungus that infect our domestic animals ,We found that the compound [A2] which contains chloride group and the compound [A4] contains triple bound group are active against gram positive bacteria, While the compound [A3] contains amine group is active against gram negative bacteria. The compound [A5] that contains Marcbtane group is effective against fungi . The compound [A1] appear that have moderate action on all bacteria (gram positive and negative) and fungi. | ||
|
Statistics Article View: 67 PDF Download: 18 |
||