A Comparative Study Between Laparoscopic Complete and Subtotal Cholecystectomy in Goats

A. Alkhilani, M.; J. Eesa, M.; I. Saleh, S.; A. Ajeel, A.

	A Comparative Study Between Laparoscopic Complete and Subtotal Cholecystectomy in Goats
Al-Anbar Journal of Veterinary Sciences
Article 1, Volume 4, Issue 0, 2011, Pages 59-68 PDF (169.89 K)
Authors
M. A. Alkhilani; M. J. Eesa; S. I. Saleh; A. A. Ajeel
Abstract
A comparison between laparoscopic complete and subtotal cholecystectomy was studied to find the deference in treating severe cholecystitis and to study the fate of the remaining part of the gallbladder in subtotal cholecystectomy. All experimental animals had induced cholecystitis by clipping the cystic duct for five days that was appeared enough for inducing cholecystitis in goats. 24 adult female goats were used in this study, which were divided randomly into two equal groups; complete laparoscopic cholecystectomy (group A) and subtotal laparoscopic cholecystectomy with cystic duct clipped only by titanium clips and leaved the cystic artery without clipping (group B) and Operations were performed under general anesthesia by using thiopental sodium at a dose of 15 mg Kg. B.W. intravenously to maintain the inhalation anesthesia by endotracheal tube with a mixture of halothane (1.5-2.5%) and oxygen (2-3%). The intraabdominal pressure with CO2 was used successfully at a low pressure 8-10 mmHg, which was enough for good vision and good manipulation of laparoscopic instruments. The physiological activities and clinical symptoms which include heart rate, respiratory rate, temperature and return to the food and water were recorded at the same time of blood samples that took for liver function tests which were including; alkaline phosphates (ALP), alanine aminotransferase (ALT), aspartate aminotransferase (AST), total serum bilirubin and C- reactive protein were measured in different intervals; before operation (zero day) and at 1hr, 1st, 3rd, 5th and 7th postoperative day. The liver function tests showed a significant elevation (P<0.05) in alkaline phosphates (ALP) and in the total bilirubin values in group B (P> 0.05) comparison with group A and no significant difference in alanine aminotransferase (ALT), aspartate aminotransferase (AST) and C- reactive protein between experimental groups as well as time intervals. The biopsies were taken at the 3rd, 7th and 15th postoperative day for histopathological of the remaining part of gallbladder in group B which showed that cholecystectomies could be performed successfully with the subtotal technique, although the superior healing through little degeneration in the remaining part of the gallbladder and best in the healing stages.

Statistics Article View: 48 PDF Download: 11