- All Journals
- Al-Qadisiyah University
- Basrah University
- Kirkuk University
- Mosul University
- The Iraqi Borad for Medical Specialization
- University of Anbar
- University of Technology
- Al Mustafa University
- Al-Zahraa University for Women
- Alnoor University
- Kunooz University
- Misan University
- Ninevah University
- Tikrit University
- University of Al-Hamdaniya
- University of Kerbala
Determination of Micro amount of Ranitidine in the Pharmaceutical Rantisam By Flame Atomic Absorption Spectrophotometry Using Palladium as Mediating Metals | ||
| journal of kerbala university | ||
| Article 1, Volume 9, Issue 0, 2013, Pages 27-35 PDF (0 K) | ||
| Abstract | ||
| It this study,the Rantidine in the three commercial pharmaceuticals was determined by in directed flame atomic absorption spectrometry(FAAS) . Ranitidine is widely used as medicament for the treatment of stomach and intestine ulcers and cases accompanied by excessive secretion. The following analytical results obtained in this research: formation of ion – pair association complex between [Pd(SCN)4]2- ranitidine and subsequent indirect AAS determination of the latter after extraction of the complex with 1,2- dichloroethane and atomization under this method has been evaluated by determining several optimal experimental conditions,namely ; as the following : PH (3.5-4.5), concentration of [Pd(SCN)4]2- equals 10 ppm , phase ratio aqueous – to – organic (7/1), time for completion of reaction in aqueous Phase is 10min, Extraction time is 3 minutes and one extraction is enough for overall removal of the complex without extrenuous interference. 1,2- dichloro ethane was used as organic solvent for extraction of the ion – pair association complex . Figures of merits: linear dynamic range (0.5-15ppm )ranitidine . RSD% (3.045). D.L (0.2283) ppm . A.S. (0.2706) ng . Erel (2.39%).Recov. % (97.61). | ||
|
Statistics Article View: 91 PDF Download: 74 |
||