The Effect of green tea extract on lipid profile, total protein and Malonaldehyde in mice Mus Musculus

M. Rasheed, R.; F. Hassan, H.; J. Hameed, M.

	The Effect of green tea extract on lipid profile, total protein and Malonaldehyde in mice Mus Musculus
Al-Anbar Journal of Veterinary Sciences
Article 1, Volume 10, Issue 2, 2017, Pages 24-33 PDF (593.8 K)
Authors
R. M. Rasheed; H. F. Hassan; M. J. Hameed
Abstract
This study was conducted to investigate the effect of using different concentrations of the green extract of green tea Camellia sinensis in the level of triglycerides, cholesterol, lipoproteins, total protein and melonaldehyde in Mus musculus. In the experiment, 50 male mice were used at a rate of 8-12 weeks with a weight of 25-20. The first group considered the control group, the distilled water was harvested, the second group had given 100 mg of the extract /g from body weight as well as the third group was given 250 mg of the extract. While the fourth group 500 mg of the extract have been dosed/g from body weight and finally the fifth group had 1000 mg dosage of the extract/ g from body weight. The green tea extract was obtained after grinding the leaves of the green tea plant using grindre and utilize the soxhelet apparatus to prepare the extract. After the expiry of the treatment period 16 days, the animals were killed and the blood was withdrawn to perform the necessary tests which included estimating the lipid profile variables in serum Which include: total cholesterol, triglyceride, high-density lipoprotein cholesterol (HDL-cholesterol), very low-density lipoprotein cholesterol (LDL), low-density lipoprotein cholesterol (VLDL) cholesterol. Also the levels of total protein, Albumin, Globulin, and Malondihyde (MDA) were estimated. The results showed a non significant decrease in the total cholesterol level, while the levels of triglycerides, LDL-Ch and VLDL-Ch decreased significantly at (P <0.05) in concurrence with the increased of the extract concentration as well as the green tea extrat elevated the total protein, albumin and the globulin levels. The MDA level decreased significantly in at (P<0.05) coincide with increased concentration of the extract. Green tea acts as an antioxidant for LDL and triglyceride, which reduces the risk of heart diseases and reduces the level of malandhydhydide, which is a sign of lipid peroxidation which produced when the cells attacking by the free radicals
Keywords
green tea extract; Lipid profile; total protein; Malonaldehyde; Mus musculus

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